Cinnamic acids and derivatives
Medchemexpress LLC Cinnamic acid | 621-82-9 | MFCD00004369 | 148.16 | 500 MG
Cinnamic acid is a chemical compound with potential applications in cancer intervention. It has shown dose-dependent growth inhibition in various tumor cells, including glioblastoma, melanoma, prostate, and lung carcinoma cells, with IC50 values ranging from 1 to 4.5 mM.
- Potential use in cancer intervention.
- Exhibits dose-dependent growth inhibition in tumor cells.
- Induces morphological changes consistent with melanocyte differentiation.
- Causes a dose-dependent loss of invasive capacity in treated tumor lines.
- Effective in glioblastoma, melanoma, prostate, and lung carcinoma cells.
2-Chlorocinnamic acid, predominantly trans, 99%, Thermo Scientific™
CAS: 3752-25-8 Molecular Formula: C9H7ClO2 Molecular Weight (g/mol): 182.603 MDL Number: MFCD00004372 InChI Key: KJRRTHHNKJBVBO-AATRIKPKSA-N Synonym: 2-chlorocinnamic acid,o-chlorocinnamic acid,3-2-chlorophenyl acrylic acid,2e-3-2-chlorophenyl acrylic acid,e-3-2-chlorophenyl acrylic acid,cinnamic acid, o-chloro,2e-3-2-chlorophenyl prop-2-enoic acid,2-propenoic acid, 3-2-chlorophenyl,e-o-chlorocinnamic acid,3-2-chlorophenyl-2-propenoic acid PubChem CID: 700642 IUPAC Name: (E)-3-(2-chlorophenyl)prop-2-enoic acid SMILES: C1=CC=C(C(=C1)C=CC(=O)O)Cl
α-Fluorocinnamic Acid 98%, Thermo Scientific™
CAS: 350-90-3 Molecular Formula: C9H7FO2 Molecular Weight (g/mol): 166.151 InChI Key: QONCEXMULRJPPY-VURMDHGXSA-N Synonym: alpha-fluorocinnamic acid,.alpha.-fluorocinnamic acid,cinnamic acid, alpha-fluoro,z-alpha-fluorocinnamic acid,2-propenoic acid, 2-fluoro-3-phenyl,z-2-fluoro-3-phenylacrylic acid,2-fluoro-3-phenyl-2-propenoic acid,2z-2-fluoro-3-phenylprop-2-enoic acid,2-fluoro-3-phenylacrylic acid,cinnamic acid, .alpha.-fluoro PubChem CID: 1550911 IUPAC Name: (Z)-2-fluoro-3-phenylprop-2-enoic acid SMILES: C1=CC=C(C=C1)C=C(C(=O)O)F
α-Cyano-βphenylacrylic Acid, MP Biomedicals
CAS: 1011-92-3 Molecular Formula: C10H7NO2 Molecular Weight (g/mol): 173.171 InChI Key: CDUQMGQIHYISOP-UHFFFAOYSA-N Synonym: 2-cyano-3-phenylacrylic acid,alpha-cyanocinnamicacid,cyanocinnamic acid,2-cyano-3-phenyl-2-propenoic acid,acmc-1b4v0,a-cyano-b-phenylacrylic acid,alpha-cyano-beta-phenyl-acrylic acid PubChem CID: 70534 IUPAC Name: 2-cyano-3-phenylprop-2-enoic acid SMILES: C1=CC=C(C=C1)C=C(C#N)C(=O)O
3,4-Dimethoxycinnamic acid, predominantly trans, 99%, Thermo Scientific™
CAS: 2316-26-9 Molecular Formula: C11H12O4 Molecular Weight (g/mol): 208.213 MDL Number: MFCD00004387 InChI Key: HJBWJAPEBGSQPR-GQCTYLIASA-N Synonym: 3,4-dimethoxycinnamic acid,dimethylcaffeic acid,caffeic acid dimethyl ether,2e-3-3,4-dimethoxyphenyl prop-2-enoic acid,dimethyl caffeic acid,e-3-3,4-dimethoxyphenyl acrylic acid,e-3,4-dimethoxycinnamic acid,unii-bvz841pvjl,2e-3-3,4-dimethoxyphenyl acrylic acid,3-3,4-dimethoxyphenyl acrylic acid PubChem CID: 717531 ChEBI: CHEBI:86549 IUPAC Name: (E)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid SMILES: COC1=C(C=C(C=C1)C=CC(=O)O)OC
m-Methoxycinnamic Acid, Predominantly trans 97%, Thermo Scientific™
CAS: 6099-04-3 Molecular Formula: C10H10O3 Molecular Weight (g/mol): 178.19 InChI Key: LZPNXAULYJPXEH-AATRIKPKSA-N Synonym: 3-methoxycinnamic acid,3-3-methoxyphenyl acrylic acid,m-methoxycinnamic acid,2e-3-3-methoxyphenyl acrylic acid,2e-3-3-methoxyphenyl prop-2-enoic acid,trans-3-methoxycinnamic acid,e-3-3-methoxyphenyl acrylic acid,trans-3-3-methoxyphenyl acrylic acid,2-propenoic acid, 3-3-methoxyphenyl-, 2e,3-3-methoxyphenyl prop-2-enoic acid PubChem CID: 637668
MP Biomedicals, Inc Sodium Cinnamate, MP Biomedicals
CAS: 538-42-1 Molecular Formula: C9H7NaO2 Molecular Weight (g/mol): 170.14 MDL Number: MFCD00064994 InChI Key: DXIHILNWDOYYCH-UHDJGPCESA-M Synonym: sodium cinnamate,fortificar,cinnamic acid, sodium salt,unii-1dkd3z3e4y,sodium 3-phenyl-2-propenoate,2-propenoic acid, 3-phenyl-, sodium salt,1dkd3z3e4y,cinnamylic acid sodium salt,sodium e-3-phenylprop-2-enoate,potassium cinnamate PubChem CID: 5462638 IUPAC Name: sodium (2E)-3-phenylprop-2-enoate SMILES: [Na+].[O-]C(=O)\C=C\C1=CC=CC=C1
4-Ethoxycinnamic Acid 98.0+%, TCI America™
CAS: 2373-79-7 Molecular Formula: C11H12O3 Molecular Weight (g/mol): 192.214 MDL Number: MFCD11040581 InChI Key: DZLOUWYGNATKKZ-VMPITWQZSA-N Synonym: 4-ethoxycinnamic acid,3-4-ethoxyphenyl acrylic acid,2e-3-4-ethoxyphenyl acrylic acid,2e-3-4-ethoxyphenyl prop-2-enoic acid,e-3-4-ethoxyphenyl acrylic acid,e-3-4-ethoxyphenyl prop-2-enoic acid,4-ethoxyphenylacrylic acid,p-ethoxycinnamic acid,ethoxyphenylacrylicacid,pubchem8239 PubChem CID: 704218 IUPAC Name: (E)-3-(4-ethoxyphenyl)prop-2-enoic acid SMILES: CCOC1=CC=C(C=C1)C=CC(=O)O
A 350619 hydrochloride, R&D Systems™
CAS: 1217201-17-6 Molecular Formula: C21H26Cl2N2OS Molecular Weight (g/mol): 425.412 InChI Key: PDVBHWZPRQFKJS-KYIGKLDSSA-N Synonym: a 350619 hydrochloride,3-2-4-chlorophenyl thiophenyl-n-4-dimethylamino butyl-2-propenamide hydrochloride,3-2-4-chlorophenyl thiophenyl-n-4-dimethylamino butyl-2-propenamidehcl PubChem CID: 56924282 IUPAC Name: (E)-3-[2-(4-chlorophenyl)sulfanylphenyl]-N-[4-(dimethylamino)butyl]prop-2-enamide;hydrochloride SMILES: CN(C)CCCCNC(=O)C=CC1=CC=CC=C1SC2=CC=C(C=C2)Cl.Cl
Clocinnamox mesylate, R&D Systems™
CAS: 117332-69-1 Molecular Formula: C30H33ClN2O7S Molecular Weight (g/mol): 601.111 InChI Key: XAXNKAGAUFXFDO-TYMYTQEGSA-N Synonym: clocinnamox mesylate,14?-p-chlorocinnamoylamino-7,8-dihydro-n-cyclopropylmethylmorphinone mesylate PubChem CID: 133655490 IUPAC Name: (E)-N-[(4S,4aR,7aS,12bS)-3-(cyclopropylmethyl)-9-hydroxy-7-oxo-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl]-3-(4-chlorophenyl)prop-2-enamide;methanesulfonic acid SMILES: CS(=O)(=O)O.C1CC1CN2CCC34C5C(=O)CCC3(C2CC6=C4C(=C(C=C6)O)O5)NC(=O)C=CC7=CC=C(C=C7)Cl
AG 825, R&D Systems™
CAS: 149092-50-2 Molecular Formula: C19H15N3O3S2 Molecular Weight (g/mol): 397.47 MDL Number: MFCD01074971 InChI Key: KXDONFLNGBQLTN-UHFFFAOYSA-N Synonym: tyrphostin ag 825,tyrphostin c15,4-hydroxy-3-methoxy-5-benzothiazolylthiomethyl benzylidenecyanoacetamide,5-benzothiazol-2-yl thiomethyl-4-hydroxy-3-methoxybenzylidenecyanoacetamide,2e-3-3-1,3-benzothiazol-2-ylsulfanyl methyl-4-hydroxy-5-methoxyphenyl-2-cyanoprop-2-enamide,tocris-1555,biomolki_000008,biomolki2_000018,bmk1-b8,tyrphostin ag PubChem CID: 6091659 ChEBI: CHEBI:75405 IUPAC Name: 3-{3-[(1,3-benzothiazol-2-ylsulfanyl)methyl]-4-hydroxy-5-methoxyphenyl}-2-cyanoprop-2-enamide SMILES: COC1=CC(C=C(C#N)C(N)=O)=CC(CSC2=NC3=CC=CC=C3S2)=C1O
Cinanserin hydrochloride, R&D Systems™
CAS: 54-84-2 Molecular Formula: C20H25ClN2OS Molecular Weight (g/mol): 376.943 InChI Key: LXGJPDKYMJJWRB-IERUDJENSA-N Synonym: cinanserin hydrochloride,cinnanserin,maptc,cinanserin hcl,unii-f65z32ki62,cinanserin hydrochloride usan,2'-3-dimethylamino propyl thio cinnamanilide hydrochloride,2'-3-dimethylamino propyl thio cinnamanilide monohydrochloride,2-propenamide, n-2-3-dimethylamino propyl thio phenyl-3-phenyl-, monohydrochloride PubChem CID: 6433141 IUPAC Name: (E)-N-[2-[3-(dimethylamino)propylsulfanyl]phenyl]-3-phenylprop-2-enamide;hydrochloride SMILES: CN(C)CCCSC1=CC=CC=C1NC(=O)C=CC2=CC=CC=C2.Cl
AG 556, R&D Systems™
CAS: 133550-41-1 Molecular Formula: C20H20N2O3 Molecular Weight (g/mol): 336.391 InChI Key: GWCNJMUSWLTSCW-SFQUDFHCSA-N Synonym: tyrphostin b56,e-2-cyano-3-3,4-dihydroxyphenyl-n-4-phenylbutyl prop-2-enamide,2e-2-cyano-3-3,4-dihydroxyphenyl-n-4-phenylbutyl prop-2-enamide,tyrphostin ag 556,tyrphostin ag556,tyrphostin ag-556,tocris-0616,tyrphostin deriv. 56,2-cyano-3-3,4-dihydroxyphenyl-n-4-phenylbutyl acrylamide,alpha-cyano-3,4-dihydroxy-n-4-phenylbutyl cinnamide PubChem CID: 5328775 IUPAC Name: (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)prop-2-enamide SMILES: C1=CC=C(C=C1)CCCCNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N